Covid-19: despite the drop in transmission, Ômicron continues to evolve

With a speed never seen before, variants of the SARS-CoV-2 virus, which causes Covid-19, were responsible for infections, hospitalizations and even the aggressiveness of the disease. As the variants became predominant, they received Greek names given by the World Health Organization (WHO): alpha, gamma and delta, for example, until arriving at Ômicron. And it is divided into different sublineages that are still circulating in Brazil and are responsible for current infections.  

According to WHO data, as of November last year, more than half of Covid-19 infections worldwide were caused by one of the five subvariants of Ômicron: BA.1, BA.2, BA.3, BA.4 and BA.5. Brazil already had all these lineages – and they continue to divide.  

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The most recent data from Todos Pela Saúde Institute (ITpS), which monitors the coronavirus positivity rate, points out that positivity remained low in September (3%), with a higher frequency of variants BA.4 and BA.5 (97,9%).

“A variant that has been circulating a lot currently is from a lineage called BE.1.1, which is a descendant of BA.5. Today there is already the BK, the BF, the BE, all derived from the BA.5. The virus spreads, undergoing different mutations, and lineages of lineages of lineages emerge. The thing takes on such a large proportion that it is difficult even for us to track it”, explained Anderson Fernandes de Brito, virologist and researcher at ITpS. 

Hundreds of variants

To date, it is estimated that more than 200 new sublineages of Ômicron and derivatives have emerged. Therefore, the greater the circulation of the virus, the greater the possibility of new mutations and variants emerging.

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“The fact is that the virus will not disappear, it will always evolve and develop new mutations. There are about two to three mutations per month. We are finally in a low transmission scenario, but we will most likely still hear about the descendants of different types of omicron”, said Brito. 

The emergence of new sublineages happens faster than science can sequence.

Importance of vaccination

The population's vaccination coverage scenario at the time a variant arrives is crucial. With the drop in vaccination coverage among people who have the extra doses, it is important to reinforce that the pandemic is not over e we cannot be unprotected, as new variants can still gain ground and spread again.  

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Source: Einstein Agency

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