They developed a computer program called Geneformer, which learns from lots of data about how genes interact in our body. This program can predict what could go wrong when we have a disease, which is very useful for understanding what happens in the affected cells.
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Geneformer is important because it helps us understand how genes change during disease. This allows scientists to identify therapeutic targets, that is, parts of genes that can be treated to combat the disease more effectively. By acting on these therapeutic targets, it is possible to treat the underlying problem of the disease, rather than just dealing with the symptoms.
An advantage of Geneformer is that it can learn from new data and tasks, without having to start everything from scratch. This is important because in some diseases, scientists have little data to work with. With the help of Geneformer, they can apply what they have already learned in other areas of biology.
This innovative approach has many applications, such as discovering possible targets for new drugs against different diseases. Scientists are excited about Geneformer's possibilities as it could help develop gene-targeted therapies in diseases where advances have been limited by a lack of information.
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It search was published in the renowned scientific journal Nature. The study was led by Christina Theodoris, researcher at Gladstone Institutes and professor at Harvard, in partnership with the Dana-Farber Cancer Institute and MIT. She worked collaboratively with other influential scientists in this field.
With the help of artificial intelligence and the understanding of genes, scientists are getting closer to developing personalized and more effective treatments for different diseases. This new technology brings hope to many people around the world.
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