Profluent has just developed OpenCRISPR-1, the first gene editor open-source created by artificial intelligence (AI) in the world, capable of editing the human genome.
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How it works
- Profluent trained large language models (LLMs) on a massive dataset from diverse CRISPR systems to generate millions of new CRISPR-like proteins never before seen in nature.
- OpenCRISPR-1 worked as well or even better than a natural editor.
- CEO Ali Madani says the success points to a future where AI “designs precisely what is needed to create a variety of tailored cures for diseases.”
- Profluent has open-sourced the model to make gene editing technology more accessible to researchers working on treatments for diseases.
Why is it important
Gene editing already had the potential to revolutionize medicine, and adding AI to the equation could take everything to a new level. Tools like OpenCRISPR-1 could, in the future, accelerate innovation, reduce costs, and improve access to life-changing treatments.
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